Nadroparin calcium
Nadroparin calcium is an oligosaccharide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
53 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombosis | D013927 | — | — | — | 1 | 7 | 10 | 7 | 24 |
| Venous thrombosis | D020246 | HP_0004936 | I82.40 | — | 1 | 6 | 9 | 6 | 21 |
| Thromboembolism | D013923 | HP_0001907 | — | — | — | 6 | 4 | 3 | 13 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 7 | 2 | 9 |
| Pulmonary embolism | D011655 | HP_0002204 | I26 | — | 1 | 2 | 4 | 3 | 9 |
| Embolism | D004617 | — | — | — | 1 | 2 | 4 | 3 | 9 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | — | 5 | 1 | 3 | 9 |
| Fibrosis | D005355 | — | — | — | — | — | 4 | 2 | 6 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | 1 | 1 | 3 | 6 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | 3 | — | 3 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | — | — | 2 | — | 4 | 6 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | — | 1 | — | 1 | 2 |
| Heart failure | D006333 | HP_0001635 | I50 | — | — | 1 | — | — | 1 |
| Respiratory insufficiency | D012131 | HP_0002093 | J96.9 | — | — | 1 | — | — | 1 |
| Extracorporeal membrane oxygenation | D015199 | — | — | — | — | 1 | — | — | 1 |
| Thrombophilia | D019851 | — | D68.59 | — | — | 1 | — | — | 1 |
| Knee injuries | D007718 | — | — | — | — | 1 | — | — | 1 |
| Carcinoma | D002277 | — | C80.0 | — | 1 | 1 | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | 1 | 1 | — | — | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Subarachnoid hemorrhage | D013345 | EFO_0000713 | I60 | — | 1 | — | — | — | 1 |
| Brain ischemia | D002545 | EFO_0003883 | I67.82 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | — | — | — | — | 2 | 2 |
| Hemostatic disorders | D020141 | — | — | — | — | — | — | 2 | 2 |
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | — | — | — | — | 1 | 1 |
| Undifferentiated connective tissue diseases | D000074079 | — | — | — | — | — | — | 1 | 1 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | — | — | 1 | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | — | — | — | 1 | 1 |
| Female genital diseases | D005831 | EFO_0009549 | N85 | — | — | — | — | 1 | 1 |
| Urogenital neoplasms | D014565 | EFO_0003863 | D07 | — | — | — | — | 1 | 1 |
| Genital diseases | D000091662 | — | — | — | — | — | — | 1 | 1 |
| Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nadroparin calcium |
| INN | nadroparin calcium |
| Description | Nadroparin (trade names Fraxiparin[e], Fraxodi, among others) is an anticoagulant belonging to a class of drugs called low molecular weight heparins (LMWHs). Nadroparin was developed by Sanofi-Synthélabo.
|
| Classification | Oligosaccharide |
| Drug class | heparin derivatives and low molecular weight (or depolymerized) heparins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109204 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB08813 |
| UNII ID | LIA7Z4002P (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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988 adverse events reported
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